New york: Major US stock indexes closed mixed on Monday. The S and P 500 rose 12.52 points, or 0.18 percent, to close at 6,852.72. The Nasdaq Composite climbed 109.77 points, or 0.46 percent, ending the session at 23,834.72. Meanwhile, the Dow Jones Industrial Average fell 218.88 points, or 0.46 percent, to 47,343.99. According to Qatar News Agency, the S and P and Nasdaq were buoyed by artificial intelligence deals involving Amazon and Nvidia, while healthcare giants such as UnitedHealth Group and Merck weighed on the Dow. Uncertainty surrounding US factory activity and the government shutdown added to market volatility, clouding expectations for the Federal Reserve's next policy move.